SELECTED PUBLICATIONS
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Zhe Chen*, Xiaomeng Zhang*, Mingxi Deng*, Chongyang Li, Thi Thuy Nguyen, Min Liu, Kun Dou, Toyotaka Ishibashi, Jiguang Wang, Yan Yan, Epigenetic reprogramming induced by Acetyl-CoA and SAM depletion is an evolutionarily ancient path to malignant growth, Disease Models & Mechanisms 2025, in press.
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Ying Wang*, Huang Rui*, Mingfeng Deng*, Jingjing He, Mingxi Deng, Toyotaka Ishibashi, Cong Yu, Zongzhao Zhai, Yan Yan, Oncogenic Ras, Yki and Notch signals converge to confer clone competitiveness through Upd2, Journal of Genetics and Genomics 2025, https://doi.org/10.1016/j.jgg.2025.04.017.
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Mingxi Deng, Ying Wang, Yan Yan, Mining cell-cell signaling in single cell transcriptomics atlases, Current Opinion in Cell Biology. 2022: DOI: 10.1016/j.ceb.2022.102101
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Mingxi Deng, Ying Wang, Lina Zhang, Yang Yang, Shengshuo Huang, Jiguang Wang, Hao Ge, Toyotaka Ishibashi, Yan Yan, Single cell transcriptomic landscapes of pattern formation, proliferation and growth in Drosophila wing imaginal discs, Development 2019 : dev.179754 doi: 10.1242/dev.179754. Highlighted in The people behind the papers interview. doi: 10.1242/dev.184309. Highlighted in Editor’s Choice: scDisc: a single cell look at a premier developmental model. Development 2019 146: e1801
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Tiantian Ji*, Lina Zhang*, Mingxi Deng, Shengshuo Huang, Ying Wang, Tri Thanh Pham, Andrew Alan Smith, Varun Sridhar, Clemens Cabernard, Jiguang Wang, Yan Yan, Dynamic MAPK signaling activity underlies a transition from growth arrest to proliferation in Drosophila scribble mutant tumors. Disease Models & Mechanisms. 2019 Aug 1. pii: dmm.040147. doi: 10.1242/dmm.040147. Highlighted in First Person interview. doi: 10.1242/dmm.041798
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An Y, Xue G, Yang S, Deng M, Zhou X, Yu W, Ishibashi T, Zhang L, Yan Y. Apical constriction is driven by a pulsatile apical myosin network in delaminating Drosophila neuroblasts. Development. 2017 Jun 15;144(12):2153-2164. Highlighted in Editor’s Choice, “A new model for single-cell delamination”.
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Wong KK, Li W, An Y, Duan Y, Li Z, Kang Y, Yan Y. β-Spectrin regulates the Hippo signaling pathway and modulates the basal actin network. J Biol Chem, 2015 Mar 6; 290(10):6397-407.
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Yan Y, Denef N, Tang C, Schupbach T. Drosophila PI4KIIIalpha is required in the follicle cells for oocyte polarization and Hippo signaling. Development. 2011 May;138(9):1697-703. • Highlighted in “Editors’ choice”: VanHook AM, Lipids Influence Hippo Signaling. Sci. Signal. 4, ec110 (2011)
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Yan Y*, Denef N*, Schupbach T. The vacuolar proton pump, V-ATPase, is required for Notch signaling and endosomal trafficking in Drosophila. Dev Cell. 2009 Sep;17(3):387-402.*These authors contributed equally to this work.